Anti-Human RAPGEF1 Polyclonal Antibody
- Cat. No.：RB9THC394014
- Price：Negotiable
- Clicks：353
Product Detail
Product Parameters
| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Human |
| Target | CRK SH3-binding GNRP, GRF2, Guanine nucleotide-releasing factor 2, Protein C3G, RAPGEF1, Rap guanine nucleotide exchange factor 1 |
| Immunogen | E. coli - derived recombinant Human RAPGEF1 (His842-Thr1077). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | Q13905 |
| Background | Rap guanine nucleotide exchange factor 1 (RAPGEF1) is a ~120 kDa protein. Guanine nucleotide-releasing protein that binds to SH3 domain of CRK and GRB2/ASH. Transduces signals from CRK to activate RAS. Involved in cell branching and adhesion mediated by BCAR1-CRK-RAPGEF1 signaling and activation of RAP1. Plays a role in the establishment of basal endothelial barrier function. Plays a role in nerve growth factor (NGF)-induced sustained activation of Rap1 and neurite outgrowth. 1. Sakakibara, A. et al. (2002) Journal of cell science 115, 4915-24. PMID: 12432078 |
| Note | For research use only |
Related Products:
| Product Name | Clicks |
|---|---|
| 新冠病毒S蛋白中和抗体ELISA半定量检测试剂盒 | 6928 |
| 新冠病毒(Delta)S蛋白中和抗体ELISA检测试剂盒 | 6440 |
| 新冠病毒(奥密克戎)S蛋白中和抗体ELISA检测试剂盒 | 6966 |
| 人抗新冠病毒S蛋白IgG抗体ELISA检测试剂盒 | 6795 |
| 人抗新冠病毒S蛋白IgM亚型抗体ELISA检测试剂盒 | 6744 |
| 人抗新冠病毒N蛋白-IgG抗体ELISA检测试剂盒 | 6430 |
| 人抗新冠病毒奥密克戎RBD蛋白IgG亚型抗体ELISA检测试剂盒 | 6709 |
| 抗新冠病毒N蛋白-IgG抗体ELISA检测试剂盒 | 6449 |
| 碱性磷酸酶-抗体快速标记试剂盒 | 6326 |
| 即用型小鼠单抗Ig类/亚类/亚型鉴定用酶标二抗套装（6种） | 6468 |
| 鼠单抗Ig类/亚类/亚型鉴定用酶标二抗套装（6种） | 6440 |
| 鼠单抗Ig类/亚类鉴定用ELISA试剂盒（6种） | 6598 |
| 鼠单抗Ig类/亚类/亚型鉴定用酶标二抗套装（8种） | 6253 |
| 即用型小鼠单抗Ig类/亚类/亚型鉴定用酶标二抗套装（8种） | 6548 |
| 鼠单抗Ig类/亚类鉴定用ELISA试剂盒（8种） | 6648 |
| 单抗融合无忧套装 | 6654 |
| 即用型单抗细胞融合/亚克培养基 | 6413 |
| Frdbio®第三代抗体生物素标记试剂盒 | 6687 |
| 通用型抗体稀释液 | 6285 |
| HRP酶标抗体稀释液 | 6501 |