| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Human, Rat, Mouse |
| Target | 40S ribosomal protein S27, MPS-1, MPS1, Metallopan-stimulin 1, RPS27, Small ribosomal subunit protein eS27 |
| Immunogen | E. coli - derived recombinant Human RPS27 (Ser11-His84). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | P42677 |
| Background | Small ribosomal subunit protein eS27 (RPS27) is a ~9 kDa protein. Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Required for proper rRNA processing and maturation of 18S rRNAs. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. 1. Anger, AM. et al. (2013) Nature 497, 80-5. PMID: 23636399 2. Vladimirov, SN. et al. (1996) European journal of biochemistry 239, 144-9. PMID: 8706699 3. Wang, R. et al. (2015) British journal of haematology 168, 854-64. PMID: 25424902 4. Singh, S. et al. (2021) Science (New York, N.Y.) 373, eabj5338. PMID: 34516797 |
| Note | For research use only |