Anti-Human PRKX Polyclonal Antibody

Form	Liquid
Host Species	Rabbit
Clonality	Polyclonal
Isotype	IgG
Purification	Purified by antigen affinity column.
Endotoxin Level	Please contact with the lab for this information.
Applications	ELISA, IHC, WB
Species Reactivity	Human
Target	EC:2.7.11.1, PKX1, PRKX, PrKX, Protein kinase PKX1, Protein kinase X, Protein kinase X-linked, Serine/threonine-protein kinase PRKX, cAMP-dependent protein kinase catalytic subunit PRKX
Immunogen	E. coli - derived recombinant Human PRKX (Ser45-Arg301).
Storage Buffer	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage Information	ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession Number	P51817
Background	cAMP-dependent protein kinase catalytic subunit PRKX is a ~40 kDa protein. Serine/threonine protein kinase regulated by and mediating cAMP signaling in cells. Acts through phosphorylation of downstream targets that may include CREB, SMAD6 and PKD1 and has multiple functions in cellular differentiation and epithelial morphogenesis. Regulates myeloid cell differentiation through SMAD6 phosphorylation. Involved in nephrogenesis by stimulating renal epithelial cell migration and tubulogenesis. Also involved in angiogenesis through stimulation of endothelial cell proliferation, migration and vascular-like structure formation.
Note	For research use only

For Research Use Only. Not for Diagnostic Procedures.

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