| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Human |
| Target | 1,4-cineole 2-exo-monooxygenase, CYP2A3, CYP2A6, CYPIIA6, Coumarin 7-hydroxylase, Cytochrome P450 2A6, Cytochrome P450 IIA3, Cytochrome P450(I), EC:1.14.14.- |
| Immunogen | E. coli - derived recombinant Human CYP2A6 (Gln25-Arg494). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | P11509 |
| Background | Cytochrome P450 2A6 (CYP2A6) is a ~56 kDa protein. Exhibits a high coumarin 7-hydroxylase activity. Can act in the hydroxylation of the anti-cancer drugs cyclophosphamide and ifosphamide. Competent in the metabolic activation of aflatoxin B1. Constitutes the major nicotine C-oxidase. Acts as a 1,4-cineole 2-exo-monooxygenase. |
| Note | For research use only |