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Anti-Human MGST3 Polyclonal Antibody

  • Cat. No.:RB9THC844014
  • Price:Negotiable
  • Clicks:139

Product Detail

Product Parameters

FormLiquid
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by antigen affinity column.
Endotoxin LevelPlease contact with the lab for this information.
ApplicationsELISA, IHC, WB
Species ReactivityHuman, Mouse
TargetEC:1.11.1.-, EC:2.5.1.-, EC:4.4.1.20, GST-3, Glutathione S-transferase 3, mitochondrial, Glutathione peroxidase MGST3, LTC4 synthase MGST3, MGST3
ImmunogenE. coli - derived recombinant Human MGST3 (Ser30-Pro70).
Storage Buffer0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage InformationELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession NumberO14880
Background

Glutathione S-transferase 3, mitochondrial (MGST3) is a ~16 kDa protein. Displays both glutathione S-transferase and glutathione peroxidase activities toward oxyeicosanoids, as part of cellular detoxification as well as synthesis of bioactive metabolites. Catalyzes conjugate addition of reduced glutathione to the alpha, beta-unsaturated C=C carbonyl group of eisosanoids such as leukotriene A4 and 15-deoxy-Delta12,14-prostaglandin J2 to form GSH adducts relevant to the inflammatory response. Catalyzes glutathione-dependent reduction of eicosanoid peroxides to yield the corresponding eicosanoid hydroxides.

1. Steinmetz-Späh, J. et al. (2022) Journal of lipid research 63, 100310. PMID: 36370807
2. Jakobsson, PJ. et al. (1997) The Journal of biological chemistry 272, 22934-9. PMID: 9278457
NoteFor research use only
For Research Use Only. Not for Diagnostic Procedures.

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