Anti-Human CYP2C18 Polyclonal Antibody
- Cat. No.：RB9THC931014
- Price：Negotiable
- Clicks：238
Product Detail
Product Parameters
| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Human |
| Target | CYP2C18, CYPIIC18, Cytochrome P450 2C18, Cytochrome P450-6b/29c, EC:1.14.14.1 |
| Immunogen | E. coli - derived recombinant Human CYP2C18 (Arg26-Val490). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | P33260 |
| Background | Cytochrome P450 2C18 (CYP2C18) is a ~55 kDa protein. A cytochrome P450 monooxygenase involved in retinoid metabolism. Hydroxylates all trans-retinoic acid (atRA) to 4-hydroxyretinoate and may modulate atRA signaling and clearance. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase). |
| Note | For research use only |
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