Anti-Human DEAF1 Polyclonal Antibody

Form	Liquid
Host Species	Rabbit
Clonality	Polyclonal
Isotype	IgG
Purification	Purified by antigen affinity column.
Endotoxin Level	Please contact with the lab for this information.
Applications	ELISA, IHC, WB
Species Reactivity	Human, Rat, Mouse
Target	DEAF1, Deformed epidermal autoregulatory factor 1 homolog, NUDR, Nuclear DEAF-1-related transcriptional regulator, SPN, Suppressin, ZMYND5, Zinc finger MYND domain-containing protein 5
Immunogen	E. coli - derived recombinant Human DEAF1 (Lys191-Asn273).
Storage Buffer	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage Information	ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession Number	O75398
Background	Deformed epidermal autoregulatory factor 1 homolog (DEAF1) is a ~59 kDa protein. Transcription factor that binds to sequence with multiple copies of 5'-TTC[CG]G-3' present in its own promoter and that of the HNRPA2B1 gene. Down-regulates transcription of these genes. Binds to the retinoic acid response element (RARE) 5'-AGGGTTCACCGAAAGTTCA-3'. Activates the proenkephalin gene independently of promoter binding, probably through protein-protein interaction. When secreted, behaves as an inhibitor of cell proliferation, by arresting cells in the G0 or G1 phase.
Note	For research use only

For Research Use Only. Not for Diagnostic Procedures.

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