Anti-Human SLURP2 Polyclonal Antibody
- Cat. No.：RB9THC987014
- Price：Negotiable
- Clicks：363
Product Detail
Product Parameters
| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Human |
| Target | SLURP-2, SLURP2, Secreted LY6/PLAUR domain-containing protein 2, Secreted Ly-6/uPAR domain-containing protein 2, Secreted Ly-6/uPAR-related protein 2 |
| Immunogen | E. coli - derived recombinant Human SLURP2 (Ile23-Asp97). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | P0DP57 |
| Background | Secreted Ly-6/uPAR domain-containing protein 2 (SLURP2) is a ~10 kDa protein. Binds and may modulate the functional properties of nicotinic and muscarinic acetylcholine receptors. May regulate keratinocytes proliferation, differentiation and apoptosis. In vitro moderately inhibits ACh-evoked currents of alpha-3:beta-2-containing nAChRs and strongly these of alpha-4:beta-2-containing nAChRs, modulates alpha-7-containing nAChRs, and inhibits nicotine-induced signaling probably implicating alpha-3:beta-4-containing nAChRs. Proposed to act on alpha-3:beta-2 and alpha-7 nAChRs in an orthosteric, and on mAChRs, such as CHRM1 and CHRM3, in an allosteric manner. |
| Note | For research use only |
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