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Anti-Human GAN Polyclonal Antibody

  • Cat. No.:RB9THD009014
  • Price:Negotiable
  • Clicks:427

Product Detail

Product Parameters

FormLiquid
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by antigen affinity column.
Endotoxin LevelPlease contact with the lab for this information.
ApplicationsELISA, IHC, WB
Species ReactivityMouse, Human
TargetGAN, GAN1, Gigaxonin, KLHL16, Kelch-like protein 16
ImmunogenE. coli - derived recombinant Human GAN (Gly270-Pro597).
Storage Buffer0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage InformationELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession NumberQ9H2C0
Background

Gigaxonin (GAN) is a ~67 kDa protein. Probable cytoskeletal component that directly or indirectly plays an important role in neurofilament architecture. May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Controls degradation of TBCB. Controls degradation of MAP1B and MAP1S, and is critical for neuronal maintenance and survival.

NoteFor research use only
For Research Use Only. Not for Diagnostic Procedures.

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