Anti-Human ZNF76 Polyclonal Antibody

Form	Liquid
Host Species	Rabbit
Clonality	Polyclonal
Isotype	IgG
Purification	Purified by antigen affinity column.
Endotoxin Level	Please contact with the lab for this information.
Applications	ELISA, IHC, WB
Species Reactivity	Rat, Human, Mouse
Target	D6S229E, ZNF523, ZNF76, Zinc finger protein 523, Zinc finger protein 76
Immunogen	E. coli - derived recombinant Human ZNF76 (Met1-Glu395).
Storage Buffer	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage Information	ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession Number	P36508
Background	Zinc finger protein 76 (ZNF76) is a ~61 kDa protein. Transcription factor that regulates expression of genes transcribed by both RNA polymerases II and III. Specifically recognizes and binds the Staf-binding site (SBS), a consensus DNA-binding motif present in many promoters. Able to activate expression of small nuclear RNA (snRNA) transcribed by RNA polymerases II and III. Also regulates expression of mRNAs and acts as a DNA-binding transcription repressor that inhibits the activity of the TATA-binding protein (TBP). 1. Kubota, H. et al. (2000) The Journal of biological chemistry 275, 28641-8. PMID: 10893243 2. Myslinski, E. et al. (1998) The Journal of biological chemistry 273, 21998-2006. PMID: 9705341 3. Zheng, G. et al. (2004) The Journal of biological chemistry 279, 42410-21. PMID: 15280358 4. Zheng, G. et al. (2006) Biochemical and biophysical research communications 339, 1069-75. PMID: 16337145
Note	For research use only

For Research Use Only. Not for Diagnostic Procedures.

Related Products: