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Anti-Human ZNF76 Polyclonal Antibody

  • Cat. No.:RB9THD020014
  • Price:Negotiable
  • Clicks:200

Product Detail

Product Parameters

FormLiquid
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by antigen affinity column.
Endotoxin LevelPlease contact with the lab for this information.
ApplicationsELISA, IHC, WB
Species ReactivityRat, Human, Mouse
TargetD6S229E, ZNF523, ZNF76, Zinc finger protein 523, Zinc finger protein 76
ImmunogenE. coli - derived recombinant Human ZNF76 (Met1-Glu395).
Storage Buffer0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage InformationELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession NumberP36508
Background

Zinc finger protein 76 (ZNF76) is a ~61 kDa protein. Transcription factor that regulates expression of genes transcribed by both RNA polymerases II and III. Specifically recognizes and binds the Staf-binding site (SBS), a consensus DNA-binding motif present in many promoters. Able to activate expression of small nuclear RNA (snRNA) transcribed by RNA polymerases II and III. Also regulates expression of mRNAs and acts as a DNA-binding transcription repressor that inhibits the activity of the TATA-binding protein (TBP).

1. Kubota, H. et al. (2000) The Journal of biological chemistry 275, 28641-8. PMID: 10893243
2. Myslinski, E. et al. (1998) The Journal of biological chemistry 273, 21998-2006. PMID: 9705341
3. Zheng, G. et al. (2004) The Journal of biological chemistry 279, 42410-21. PMID: 15280358
4. Zheng, G. et al. (2006) Biochemical and biophysical research communications 339, 1069-75. PMID: 16337145
NoteFor research use only
For Research Use Only. Not for Diagnostic Procedures.

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