| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Human |
| Target | CI-19kD, CI-PGIV, Complex I-19kD, Complex I-PGIV, NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8, NADH-ubiquinone oxidoreductase 19 kDa subunit, NDUFA8 |
| Immunogen | E. coli - derived recombinant Human NDUFA8 (Val18-Val118). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | P51970 |
| Background | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (NDUFA8) is a ~20 kDa protein. Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. 1. Stroud, DA. et al. (2016) Nature 538, 123-126. PMID: 27626371 2. Yatsuka, Y. et al. (2020) Clinical genetics 98, 155-165. PMID: 32385911 3. Tort, F. et al. (2020) Molecular genetics and metabolism 131, 349-357. PMID: 33153867 |
| Note | For research use only |