Anti-Human UBE2G2 Polyclonal Antibody

Form	Liquid
Host Species	Rabbit
Clonality	Polyclonal
Isotype	IgG
Purification	Purified by antigen affinity column.
Endotoxin Level	Please contact with the lab for this information.
Applications	ELISA, IHC, WB
Species Reactivity	Mouse, Human
Target	E2 ubiquitin-conjugating enzyme G2, EC:2.3.2.23, UBC7, UBE2G2, Ubiquitin carrier protein G2, Ubiquitin-conjugating enzyme E2 G2, Ubiquitin-protein ligase G2
Immunogen	E. coli - derived recombinant Human UBE2G2 (Met1-Leu165).
Storage Buffer	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage Information	ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession Number	P60604
Background	Ubiquitin-conjugating enzyme E2 G2 (UBE2G2) is a ~18 kDa protein. Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination. Involved in endoplasmic reticulum-associated degradation (ERAD). Required for sterol-induced ubiquitination of 3-hydroxy-3-methylglutaryl coenzyme A reductase and its subsequent proteasomal degradation. 1. David, Y. et al. (2010) The Journal of biological chemistry 285, 8595-604. PMID: 20061386 2. Sato, T. et al. (2012) Molecular cell 47, 99-110. PMID: 22607976 3. Jo, Y. et al. (2013) Molecular biology of the cell 24, 169-83. PMID: 23223569
Note	For research use only

For Research Use Only. Not for Diagnostic Procedures.

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