Anti-Human MBLAC1 Polyclonal Antibody
- Cat. No.：RB9THD132014
- Price：Negotiable
- Clicks：182
Product Detail
Product Parameters
| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Human |
| Target | EC:3.1.27.-, Endoribonuclease MBLAC1, MBLAC1, Metallo-beta-lactamase domain-containing protein 1 |
| Immunogen | E. coli - derived recombinant Human MBLAC1 (Arg2-Arg236). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | A4D2B0 |
| Background | Metallo-beta-lactamase domain-containing protein 1 (MBLAC1) is a ~27 kDa protein. Endoribonuclease that catalyzes the hydrolysis of histone-coding pre-mRNA 3'-end. Involved in histone pre-mRNA processing during the S-phase of the cell cycle, which is required for entering/progressing through S-phase. Cleaves histone pre-mRNA at a major and a minor cleavage site after the 5'-ACCCA-3' and the 5'-ACCCACA-3' sequence, respectively, and located downstream of the stem-loop. May require the presence of the HDE element located at the histone pre-RNA 3'-end to avoid non-specific cleavage. 1. Pettinati, I. et al. (2018) eLife 7. PMID: 30507380 |
| Note | For research use only |
Related Products: