Anti-Human PRPF6 Polyclonal Antibody

Form	Liquid
Host Species	Rabbit
Clonality	Polyclonal
Isotype	IgG
Purification	Purified by antigen affinity column.
Endotoxin Level	Please contact with the lab for this information.
Applications	ELISA, IHC, WB
Species Reactivity	Rat, Human, Mouse
Target	ANT-1, Androgen receptor N-terminal domain-transactivating protein 1, C20orf14, PRP6 homolog, PRPF6, Pre-mRNA-processing factor 6, U5 snRNP-associated 102 kDa protein, U5-102 kDa protein
Immunogen	E. coli - derived recombinant Human PRPF6 (Lys606-Phe941).
Storage Buffer	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage Information	ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession Number	O94906
Background	Pre-mRNA-processing factor 6 (PRPF6) is a ~106 kDa protein. Involved in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex, one of the building blocks of the spliceosome. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but does not affect estrogen-induced transactivation. 1. Schneider, M. et al. (2010) Nature structural & molecular biology 17, 216-21. PMID: 20118938 2. Tanackovic, G. et al. (2011) American journal of human genetics 88, 643-9. PMID: 21549338 3. Bertram, K. et al. (2017) Cell 170, 701-713.e11. PMID: 28781166
Note	For research use only

For Research Use Only. Not for Diagnostic Procedures.

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