Anti-Human PRPF6 Polyclonal Antibody
- Cat. No.：RB9THD153014
- Price：Negotiable
- Clicks：317
Product Detail
Product Parameters
| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Rat, Human, Mouse |
| Target | ANT-1, Androgen receptor N-terminal domain-transactivating protein 1, C20orf14, PRP6 homolog, PRPF6, Pre-mRNA-processing factor 6, U5 snRNP-associated 102 kDa protein, U5-102 kDa protein |
| Immunogen | E. coli - derived recombinant Human PRPF6 (Lys606-Phe941). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | O94906 |
| Background | Pre-mRNA-processing factor 6 (PRPF6) is a ~106 kDa protein. Involved in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex, one of the building blocks of the spliceosome. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but does not affect estrogen-induced transactivation. 1. Schneider, M. et al. (2010) Nature structural & molecular biology 17, 216-21. PMID: 20118938 2. Tanackovic, G. et al. (2011) American journal of human genetics 88, 643-9. PMID: 21549338 3. Bertram, K. et al. (2017) Cell 170, 701-713.e11. PMID: 28781166 |
| Note | For research use only |
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