| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Human, Mouse |
| Target | BNC, BNC1, Zinc finger protein basonuclin-1 |
| Immunogen | E. coli - derived recombinant Human BNC1 (Thr38-Asn250). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | Q01954 |
| Background | Zinc finger protein basonuclin-1 (BNC1) is a ~110 kDa protein. Transcriptional activator. It is likely involved in the regulation of keratinocytes terminal differentiation in squamous epithelia and hair follicles. Required for the maintenance of spermatogenesis. It is involved in the positive regulation of oocyte maturation, probably acting through the control of BMP15 levels and regulation of AKT signaling cascade. May also play a role in the early development of embryos. 1. Tseng, H. et al. (1994) The Journal of cell biology 126, 495-506. PMID: 8034748 2. Zhang, D. et al. (2018) Human molecular genetics 27, 3787-3800. PMID: 30010909 |
| Note | For research use only |