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Anti-Human BNC1 Polyclonal Antibody

  • Cat. No.:RB9THD166014
  • Price:Negotiable
  • Clicks:275

Product Detail

Product Parameters

FormLiquid
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by antigen affinity column.
Endotoxin LevelPlease contact with the lab for this information.
ApplicationsELISA, IHC, WB
Species ReactivityHuman, Mouse
TargetBNC, BNC1, Zinc finger protein basonuclin-1
ImmunogenE. coli - derived recombinant Human BNC1 (Thr38-Asn250).
Storage Buffer0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage InformationELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession NumberQ01954
Background

Zinc finger protein basonuclin-1 (BNC1) is a ~110 kDa protein. Transcriptional activator. It is likely involved in the regulation of keratinocytes terminal differentiation in squamous epithelia and hair follicles. Required for the maintenance of spermatogenesis. It is involved in the positive regulation of oocyte maturation, probably acting through the control of BMP15 levels and regulation of AKT signaling cascade. May also play a role in the early development of embryos.

1. Tseng, H. et al. (1994) The Journal of cell biology 126, 495-506. PMID: 8034748
2. Zhang, D. et al. (2018) Human molecular genetics 27, 3787-3800. PMID: 30010909
NoteFor research use only
For Research Use Only. Not for Diagnostic Procedures.

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