Anti-Human SOS2 Polyclonal Antibody
- Cat. No.：RB9THD170014
- Price：Negotiable
- Clicks：509
Product Detail
Product Parameters
| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Human, Mouse |
| Target | SOS-2, SOS2, Son of sevenless homolog 2 |
| Immunogen | E. coli - derived recombinant Human SOS2 (Met1-Asn561). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | Q07890 |
| Background | Son of sevenless homolog 2 (SOS2) is a ~152 kDa protein. Acts as guanine nucleotide exchange factor (GEF) for RAS proteins. Catalyzes the GDP-to-GTP exchange, resulting in an increase of the active GTP-bound form of HRAS. Acts as a key modulator of PI3K-AKT signaling. 1. Liu, AM. et al. (2010) Cellular signalling 22, 1448-58. PMID: 20639119 |
| Note | For research use only |
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