Anti-Human INCA1 Polyclonal Antibody
- Cat. No.：RB9THD173014
- Price：Negotiable
- Clicks：272
Product Detail
Product Parameters
| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Human |
| Target | INCA1, Inhibitor of CDK interacting with cyclin A1, Protein INCA1 |
| Immunogen | E. coli - derived recombinant Human INCA1 (Gln2-Glu236). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | Q0VD86 |
| Background | Protein INCA1 is a ~26 kDa protein. Binds to CDK2-bound cyclins and inhibits the kinase activity of CDK2; binding to cyclins is critical for its function as CDK inhibitor. Inhibits cell growth and cell proliferation and may play a role in cell cycle control. Required for ING5-mediated regulation of S-phase progression, enhancement of Fas-induced apoptosis and inhibition of cell growth. 1. Bäumer, N. et al. (2011) The Journal of biological chemistry 286, 28210-22. PMID: 21540187 |
| Note | For research use only |
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