Anti-Human BNIP1 Polyclonal Antibody

Form	Liquid
Host Species	Rabbit
Clonality	Polyclonal
Isotype	IgG
Purification	Purified by antigen affinity column.
Endotoxin Level	Please contact with the lab for this information.
Applications	ELISA, IHC, WB
Species Reactivity	Mouse, Rat, Human
Target	BCL2/adenovirus E1B 19 kDa protein-interacting protein 1, BNIP1, NIP1, SEC20L, TRG-8, Transformation-related gene 8 protein, Vesicle transport protein SEC20
Immunogen	E. coli - derived recombinant Human BNIP1 (Met1-Leu199).
Storage Buffer	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage Information	ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession Number	Q12981
Background	Vesicle transport protein SEC20 (BNIP1) is a ~26 kDa protein. As part of a SNARE complex may be involved in endoplasmic reticulum membranes fusion and be required for the maintenance of endoplasmic reticulum organization. Also plays a role in apoptosis. It is for instance required for endoplasmic reticulum stress-induced apoptosis. As a substrate of RNF185 interacting with SQSTM1, might also be involved in mitochondrial autophagy (Probable). 1. Nakajima, K. et al. (2004) The EMBO journal 23, 3216-26. PMID: 15272311 2. Wang, P. et al. (2013) Cellular signalling 25, 2320-33. PMID: 23896122 3. Boyd, JM. et al. (1994) Cell 79, 341-51. PMID: 7954800
Note	For research use only

For Research Use Only. Not for Diagnostic Procedures.

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