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Anti-Human BNIP1 Polyclonal Antibody

  • Cat. No.:RB9THD183014
  • Price:Negotiable
  • Clicks:365

Product Detail

Product Parameters

FormLiquid
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by antigen affinity column.
Endotoxin LevelPlease contact with the lab for this information.
ApplicationsELISA, IHC, WB
Species ReactivityMouse, Rat, Human
TargetBCL2/adenovirus E1B 19 kDa protein-interacting protein 1, BNIP1, NIP1, SEC20L, TRG-8, Transformation-related gene 8 protein, Vesicle transport protein SEC20
ImmunogenE. coli - derived recombinant Human BNIP1 (Met1-Leu199).
Storage Buffer0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage InformationELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession NumberQ12981
Background

Vesicle transport protein SEC20 (BNIP1) is a ~26 kDa protein. As part of a SNARE complex may be involved in endoplasmic reticulum membranes fusion and be required for the maintenance of endoplasmic reticulum organization. Also plays a role in apoptosis. It is for instance required for endoplasmic reticulum stress-induced apoptosis. As a substrate of RNF185 interacting with SQSTM1, might also be involved in mitochondrial autophagy (Probable).

1. Nakajima, K. et al. (2004) The EMBO journal 23, 3216-26. PMID: 15272311
2. Wang, P. et al. (2013) Cellular signalling 25, 2320-33. PMID: 23896122
3. Boyd, JM. et al. (1994) Cell 79, 341-51. PMID: 7954800
NoteFor research use only
For Research Use Only. Not for Diagnostic Procedures.

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