| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Human |
| Target | FAST kinase domain-containing protein 3, mitochondrial, FASTKD3 |
| Immunogen | E. coli - derived recombinant Human FASTKD3 (Val84-Tyr516). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | Q14CZ7 |
| Background | FAST kinase domain-containing protein 3, mitochondrial (FASTKD3) is a ~75 kDa protein. Required for normal mitochondrial respiration. Increases steady-state levels and half-lives of a subset of mature mitochondrial mRNAs MT-ND2, MT-ND3, MT-CYTB, MT-CO2, and MT-ATP8/6. Promotes MT-CO1 mRNA translation and increases mitochondrial complex IV assembly and activity. 1. Simarro, M. et al. (2010) Biochemical and biophysical research communications 401, 440-6. PMID: 20869947 2. Boehm, E. et al. (2016) The Journal of biological chemistry 291, 25877-25887. PMID: 27789713 |
| Note | For research use only |