Anti-Human TAF5 Polyclonal Antibody
- Cat. No.：RB9THD242014
- Price：Negotiable
- Clicks：150
Product Detail
Product Parameters
| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Mouse, Human |
| Target | TAF(II)100, TAF2D, TAF5, TAFII-100, TAFII100, Transcription initiation factor TFIID 100 kDa subunit, Transcription initiation factor TFIID subunit 5 |
| Immunogen | E. coli - derived recombinant Human TAF5 (Leu458-Gln800). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | Q15542 |
| Background | Transcription initiation factor TFIID subunit 5 (TAF5) is a ~86 kDa protein. The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription. TFIID recognizes and binds promoters with or without a TATA box via its subunit TBP, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC). The TFIID complex consists of TBP and TBP-associated factors (TAFs), including TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13. The TFIID complex structure can be divided into 3 modules TFIID-A, TFIID-B, and TFIID-C. TAF5 is involved in two modules of TFIID, in TFIID-A together with TAF3 and TBP, and in TFIID-B with TAF8. 1. Chen, X. et al. (2021) Science (New York, N.Y.) 372. PMID: 33795473 2. Dubrovskaya, V. et al. (1996) The EMBO journal 15, 3702-12. PMID: 8758937 3. Tanese, N. et al. (1996) Proceedings of the National Academy of Sciences of the United States of America 93, 13611-6. PMID: 8942982 4. Tao, Y. et al. (1997) The Journal of biological chemistry 272, 6714-21. PMID: 9045704 |
| Note | For research use only |
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