| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Rat, Human |
| Target | CDI1, CDK2-associated dual-specificity phosphatase, CDKN3, CIP2, Cyclin-dependent kinase inhibitor 3, Cyclin-dependent kinase interactor 1, Cyclin-dependent kinase-interacting protein 2, EC:3.1.3.16, |
| Immunogen | E. coli - derived recombinant Human CDKN3 (His28-Arg212). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | Q16667 |
| Background | Cyclin-dependent kinase inhibitor 3 (CDKN3) is a ~23 kDa protein. May play a role in cell cycle regulation. Dual specificity CC phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues. Dephosphorylates CDK2 at 'Thr-160' in a cyclin-dependent manner. 1. Hannon, GJ. et al. (1994) Proceedings of the National Academy of Sciences of the United States of America 91, 1731-5. PMID: 8127873 2. Gyuris, J. et al. (1993) Cell 75, 791-803. PMID: 8242750 3. Poon, RY. et al. (1995) Science (New York, N.Y.) 270, 90-3. PMID: 7569954 |
| Note | For research use only |