Anti-Human PYDC2 Polyclonal Antibody
- Cat. No.：RB9THD282014
- Price：Negotiable
- Clicks：553
Product Detail
Product Parameters
| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Human |
| Target | POP2, PYDC2, Pyrin domain-containing protein 2, Pyrin-only protein 2, cPOP2, cellular POP2 |
| Immunogen | E. coli - derived recombinant Human PYDC2 (Met1-Pro97). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | Q56P42 |
| Background | Pyrin domain-containing protein 2 (PYDC2) is a ~10 kDa protein. May play a role in innate immunity by disrupting the interaction between PYCARD and NLRP3, thereby regulating the NLRP3 inflammasome. May also inhibit NF-kappa-B signaling distally by affecting the nuclear accumulation of RELA. 1. Dorfleutner, A. et al. (2007) Infection and immunity 75, 1484-92. PMID: 17178784 2. Bedoya, F. et al. (2007) Journal of immunology (Baltimore, Md. : 1950) 178, 3837-45. PMID: 17339483 3. Porter, KA. et al. (2014) Genes and immunity 15, 392-403. PMID: 24871464 |
| Note | For research use only |
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