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Anti-Human TAF3 Polyclonal Antibody

  • Cat. No.:RB9THD303014
  • Price:Negotiable
  • Clicks:430

Product Detail

Product Parameters

FormLiquid
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by antigen affinity column.
Endotoxin LevelPlease contact with the lab for this information.
ApplicationsELISA, IHC, WB
Species ReactivityMouse, Human
Target140 kDa TATA box-binding protein-associated factor, TAF(II)140, TAF140, TAF3, TAFII-140, TAFII140, TBP-associated factor 3, Transcription initiation factor TFIID 140 kDa subunit, Transcription initiat
ImmunogenE. coli - derived recombinant Human TAF3 (Cys2-Phe99).
Storage Buffer0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage InformationELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession NumberQ5VWG9
Background

Transcription initiation factor TFIID subunit 3 (TAF3) is a ~103 kDa protein. The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription. TFIID recognizes and binds promoters with or without a TATA box via its subunit TBP, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC). The TFIID complex consists of TBP and TBP-associated factors (TAFs), including TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13. The TFIID complex structure can be divided into 3 modules TFIID-A, TFIID-B, and TFIID-C. TAF3 forms the TFIID-A module together with TAF5 and TBP.

1. Chen, X. et al. (2021) Science (New York, N.Y.) 372. PMID: 33795473
2. Gangloff, YG. et al. (2001) Molecular and cellular biology 21, 5109-21. PMID: 11438666
NoteFor research use only
For Research Use Only. Not for Diagnostic Procedures.

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