Anti-Human TSHZ3 Polyclonal Antibody

Form	Liquid
Host Species	Rabbit
Clonality	Polyclonal
Isotype	IgG
Purification	Purified by antigen affinity column.
Endotoxin Level	Please contact with the lab for this information.
Applications	ELISA, IHC, WB
Species Reactivity	Human, Mouse, Rat
Target	KIAA1474, TSH3, TSHZ3, Teashirt homolog 3, ZNF537, Zinc finger protein 537
Immunogen	E. coli - derived recombinant Human TSHZ3 (Trp898-Gln1081).
Storage Buffer	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage Information	ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession Number	Q63HK5
Background	Teashirt homolog 3 (TSHZ3) is a ~118 kDa protein. Transcriptional regulator involved in developmental processes. Functions in association with APBB1, SET and HDAC factors as a transcriptional repressor, that inhibits the expression of CASP4. TSHZ3-mediated transcription repression involves the recruitment of histone deacetylases HDAC1 and HDAC2. Associates with chromatin in a region surrounding the CASP4 transcriptional start site(s). Regulates the development of neurons involved in both respiratory rhythm and airflow control. 1. Kajiwara, Y. et al. (2009) PloS one 4, e5071. PMID: 19343227
Note	For research use only

For Research Use Only. Not for Diagnostic Procedures.

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