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Anti-Human TSHZ3 Polyclonal Antibody

  • Cat. No.:RB9THD311014
  • Price:Negotiable
  • Clicks:525

Product Detail

Product Parameters

FormLiquid
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by antigen affinity column.
Endotoxin LevelPlease contact with the lab for this information.
ApplicationsELISA, IHC, WB
Species ReactivityHuman, Mouse, Rat
TargetKIAA1474, TSH3, TSHZ3, Teashirt homolog 3, ZNF537, Zinc finger protein 537
ImmunogenE. coli - derived recombinant Human TSHZ3 (Trp898-Gln1081).
Storage Buffer0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage InformationELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession NumberQ63HK5
Background

Teashirt homolog 3 (TSHZ3) is a ~118 kDa protein. Transcriptional regulator involved in developmental processes. Functions in association with APBB1, SET and HDAC factors as a transcriptional repressor, that inhibits the expression of CASP4. TSHZ3-mediated transcription repression involves the recruitment of histone deacetylases HDAC1 and HDAC2. Associates with chromatin in a region surrounding the CASP4 transcriptional start site(s). Regulates the development of neurons involved in both respiratory rhythm and airflow control.

1. Kajiwara, Y. et al. (2009) PloS one 4, e5071. PMID: 19343227
NoteFor research use only
For Research Use Only. Not for Diagnostic Procedures.

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