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Anti-Human RADX Polyclonal Antibody

  • Cat. No.:RB9THD368014
  • Price:Negotiable
  • Clicks:251

Product Detail

Product Parameters

FormLiquid
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by antigen affinity column.
Endotoxin LevelPlease contact with the lab for this information.
ApplicationsELISA, IHC, WB
Species ReactivityHuman
TargetCXorf57, RADX, RPA-related and RAD51-antagonist, X-chromosome, RPA-related protein RADX
ImmunogenE. coli - derived recombinant Human RADX (Ser44-Asn357).
Storage Buffer0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage InformationELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession NumberQ6NSI4
Background

RPA-related protein RADX is a ~97 kDa protein. Single-stranded DNA-binding protein recruited to replication forks to maintain genome stability. Prevents fork collapse by antagonizing the accumulation of RAD51 at forks to ensure the proper balance of fork remodeling and protection without interfering with the capacity of cells to complete homologous recombination of double-strand breaks.

1. Dungrawala, H. et al. (2017) Molecular cell 67, 374-386.e5. PMID: 28735897
NoteFor research use only
For Research Use Only. Not for Diagnostic Procedures.

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