| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Mouse, Human |
| Target | EH domain-containing protein 4, EHD4, HCA10, HCA11, Hepatocellular carcinoma-associated protein 10/11, PAST homolog 4, PAST4 |
| Immunogen | E. coli - derived recombinant Human EHD4 (Thr23-Thr407). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | Q9H223 |
| Background | EH domain-containing protein 4 (EHD4) is a ~61 kDa protein. ATP- and membrane-binding protein that probably controls membrane reorganization/tubulation upon ATP hydrolysis. Plays a role in early endosomal transport. During sprouting angiogenesis, in complex with PACSIN2 and MICALL1, forms recycling endosome-like tubular structure at asymmetric adherens junctions to control CDH5 trafficking. 1. George, M. et al. (2007) BMC cell biology 8, 3. PMID: 17233914 2. Sharma, M. et al. (2008) Traffic (Copenhagen, Denmark) 9, 995-1018. PMID: 18331452 |
| Note | For research use only |