Anti-Mouse DYNC2I2 Polyclonal Antibody

Form	Liquid
Host Species	Rabbit
Clonality	Polyclonal
Isotype	IgG
Purification	Purified by antigen affinity column.
Endotoxin Level	Please contact with the lab for this information.
Applications	ELISA, IHC, WB
Species Reactivity	Mouse
Target	Cytoplasmic dynein 2 intermediate chain 2, DYNC2I2, Dynein 2 intermediate chain 2, WD repeat-containing protein 34, WDR34
Immunogen	E. coli - derived recombinant Mouse DYNC2I2 (Val147-Thr537).
Storage Buffer	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage Information	ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession Number	Q5U4F6
Background	Cytoplasmic dynein 2 intermediate chain 2 (DYNC2I2) is a ~58 kDa protein. Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 2 complex (dynein-2 complex), a motor protein complex that drives the movement of cargos along microtubules within cilia and flagella in concert with the intraflagellar transport (IFT) system. DYNC2I2 plays a major role in retrograde ciliary protein trafficking and in ciliogenesis. Required also to maintain a functional transition zone. 1. Wu, C. et al. (2017) Human molecular genetics 26, 2386-2397. PMID: 28379358
Note	For research use only

For Research Use Only. Not for Diagnostic Procedures.

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