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Anti-Mouse DYNC2I2 Polyclonal Antibody

  • Cat. No.:RB9TMD460014
  • Price:Negotiable
  • Clicks:269

Product Detail

Product Parameters

FormLiquid
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by antigen affinity column.
Endotoxin LevelPlease contact with the lab for this information.
ApplicationsELISA, IHC, WB
Species ReactivityMouse
TargetCytoplasmic dynein 2 intermediate chain 2, DYNC2I2, Dynein 2 intermediate chain 2, WD repeat-containing protein 34, WDR34
ImmunogenE. coli - derived recombinant Mouse DYNC2I2 (Val147-Thr537).
Storage Buffer0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage InformationELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession NumberQ5U4F6
Background

Cytoplasmic dynein 2 intermediate chain 2 (DYNC2I2) is a ~58 kDa protein. Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 2 complex (dynein-2 complex), a motor protein complex that drives the movement of cargos along microtubules within cilia and flagella in concert with the intraflagellar transport (IFT) system. DYNC2I2 plays a major role in retrograde ciliary protein trafficking and in ciliogenesis. Required also to maintain a functional transition zone.

1. Wu, C. et al. (2017) Human molecular genetics 26, 2386-2397. PMID: 28379358
NoteFor research use only
For Research Use Only. Not for Diagnostic Procedures.

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