| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Mouse |
| Target | Cytoplasmic dynein 2 intermediate chain 2, DYNC2I2, Dynein 2 intermediate chain 2, WD repeat-containing protein 34, WDR34 |
| Immunogen | E. coli - derived recombinant Mouse DYNC2I2 (Val147-Thr537). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | Q5U4F6 |
| Background | Cytoplasmic dynein 2 intermediate chain 2 (DYNC2I2) is a ~58 kDa protein. Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 2 complex (dynein-2 complex), a motor protein complex that drives the movement of cargos along microtubules within cilia and flagella in concert with the intraflagellar transport (IFT) system. DYNC2I2 plays a major role in retrograde ciliary protein trafficking and in ciliogenesis. Required also to maintain a functional transition zone. 1. Wu, C. et al. (2017) Human molecular genetics 26, 2386-2397. PMID: 28379358 |
| Note | For research use only |