Anti-Mouse DGAT1 Polyclonal Antibody
- Cat. No.：RB9TMF844014
- Price：Negotiable
- Clicks：401
Product Detail
Product Parameters
| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Mouse, Rat |
| Target | ACAT-related gene product 1, AGRP1, ARAT, Acyl-CoA retinol O-fatty-acyltransferase, DGAT, DGAT1, Diacylglycerol O-acyltransferase 1, Diglyceride acyltransferase, EC:2.3.1.20, EC:2.3.1.76, Retinol O-fa |
| Immunogen | E. coli - derived recombinant Mouse DGAT1 (Gly2-Ser92). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | Q9Z2A7 |
| Background | Diacylglycerol O-acyltransferase 1 (DGAT1) is a ~56 kDa protein. Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. Highly expressed in epithelial cells of the small intestine and its activity is essential for the absorption of dietary fats. In liver, plays a role in esterifying exogenous fatty acids to glycerol, and is required to synthesize fat for storage. Also present in female mammary glands, where it produces fat in the milk. May be involved in VLDL (very low density lipoprotein) assembly. 1. Yen, CL. et al. (2005) Journal of lipid research 46, 1502-11. PMID: 15834126 2. Shih, MY. et al. (2009) The Journal of biological chemistry 284, 4292-9. PMID: 19028692 3. McFie, PJ. et al. (2010) The Journal of biological chemistry 285, 37377-87. PMID: 20876538 4. Qi, J. et al. (2012) Journal of lipid research 53, 1106-16. PMID: 22493088 5. Ma, Z. et al. (2017) Journal of lipid research 58, 1091-1099. PMID: 28420705 6. Buhman, KK. et al. (2002) The Journal of biological chemistry 277, 25474-9. PMID: 11959864 |
| Note | For research use only |
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