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Anti-Mouse Arl13b Polyclonal Antibody

  • Cat. No.:RB9TMS942014
  • Price:Negotiable
  • Clicks:354

Product Detail

Product Parameters

FormLiquid
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by antigen affinity column.
Endotoxin LevelPlease contact with the lab for this information.
ApplicationsELISA, IHC, WB
Species ReactivityHuman, Mouse
TargetADP-ribosylation factor-like protein 13B, ADP-ribosylation factor-like protein 2-like 1, ARL13B, ARL2-like protein 1, ARL2L1
ImmunogenE. coli - derived recombinant Mouse Arl13b (Met1-Ser241).
Storage Buffer0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage InformationELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession NumberQ640N2
Background

ADP-ribosylation factor-like protein 13B (Arl13b) is a ~48 kDa protein. Cilium-specific protein required to control the microtubule-based, ciliary axoneme structure. May act by maintaining the association between IFT subcomplexes A and B. Binds GTP but is not able to hydrolyze it; the GTPase activity remains unclear. Required to pattern the neural tube. Involved in cerebral cortex development: required for the initial formation of a polarized radial glial scaffold, the first step in the construction of the cerebral cortex, by regulating ciliary signaling.

1. Higginbotham, H. et al. (2013) Nature neuroscience 16, 1000-7. PMID: 23817546
2. Higginbotham, H. et al. (2012) Developmental cell 23, 925-38. PMID: 23153492
NoteFor research use only
For Research Use Only. Not for Diagnostic Procedures.

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