Anti-Mouse LGALS8 Polyclonal Antibody
- Cat. No.：RB9TMT448014
- Price：Negotiable
- Clicks：535
Product Detail
Product Parameters
| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Mouse |
| Target | Gal-8, Galectin-8, LGALS8, PCTA-1, Po66 carbohydrate-binding protein, Po66-CBP, Prostate carcinoma tumor antigen 1 |
| Immunogen | E. coli - derived recombinant Mouse LGALS8 (Met1-Ala163). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | Q9JL15 |
| Background | Galectin-8 (LGALS8) is a ~36 kDa protein. Beta-galactoside-binding lectin that acts as a sensor of membrane damage caused by infection and restricts the proliferation of infecting pathogens by targeting them for autophagy. Detects membrane rupture by binding beta-galactoside ligands located on the lumenal side of the endosome membrane; these ligands becoming exposed to the cytoplasm following rupture. Restricts infection by initiating autophagy via interaction with CALCOCO2/NDP52. Required to restrict infection of bacterial invasion such as S.typhimurium. Also required to restrict infection of Picornaviridae viruses. |
| Note | For research use only |
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