| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Mouse, Human |
| Target | 70 kDa ribosomal protein S6 kinase 2, EC:2.7.11.1, P70S6K2, RPS6KB2, Ribosomal protein S6 kinase beta-2, S6 kinase-related kinase, S6K-beta, S6K-beta-2, S6K2, SRK, STK14B, Serine/threonine-protein kin |
| Immunogen | E. coli - derived recombinant Human RPS6KB2 (Arg61-Ser403). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | Q9UBS0 |
| Background | Ribosomal protein S6 kinase beta-2 (RPS6KB2) is a ~53 kDa protein. Phosphorylates specifically ribosomal protein S6. Seems to act downstream of mTOR signaling in response to growth factors and nutrients to promote cell proliferation, cell growth and cell cycle progression in an alternative pathway regulated by MEAK7. 1. Nguyen, JT. et al. (2018) Science advances 4, eaao5838. PMID: 29750193 |
| Note | For research use only |