Anti-Mouse GP6 Polyclonal Antibody
- Cat. No.：RB9TMV664014
- Price：Negotiable
- Clicks：325
Product Detail
Product Parameters
| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Mouse |
| Target | GP6, GPVI, Glycoprotein 6, Platelet glycoprotein VI |
| Immunogen | E. coli - derived recombinant Mouse GP6 (Ser101-Leu206). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | P0C191 |
| Background | Platelet glycoprotein VI (GP6) is a ~34 kDa protein. Collagen receptor involved in collagen-induced platelet adhesion and activation. Plays a key role in platelet procoagulant activity and subsequent thrombin and fibrin formation. This procoagulant function may contribute to arterial and venous thrombus formation. The signaling pathway involves the FcR gamma-chain, the Src kinases (likely FYN or LYN) and SYK, the adapter protein LAT and leads to the activation of PLCG2. 1. Lockyer, S. et al. (2006) Thrombosis research 118, 371-80. PMID: 16139873 2. Pokidysheva, E. et al. (2014) Proceedings of the National Academy of Sciences of the United States of America 111, 161-6. PMID: 24368846 |
| Note | For research use only |
Related Products: