Anti-Human PURA Polyclonal Antibody

Form	Liquid
Host Species	Rabbit
Clonality	Polyclonal
Isotype	IgG
Purification	Purified by antigen affinity column.
Endotoxin Level	Please contact with the lab for this information.
Applications	ELISA, IHC, WB
Species Reactivity	Mouse, Human
Target	PUR1, PURA, Purine-rich single-stranded DNA-binding protein alpha, Transcriptional activator protein Pur-alpha
Immunogen	E. coli - derived recombinant Human PURA (Gln59-Tyr209).
Storage Buffer	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage Information	ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession Number	Q00577
Background	Transcriptional activator protein Pur-alpha (PURA) is a ~34 kDa protein. This is a probable transcription activator that specifically binds the purine-rich single strand of the PUR element located upstream of the MYC gene. May play a role in the initiation of DNA replication and in recombination. 1. Bergemann, AD. et al. (1992) Molecular and cellular biology 12, 5673-82. PMID: 1448097 2. Graebsch, A. et al. (2010) PloS one 5, e13402. PMID: 20976240
Note	For research use only

For Research Use Only. Not for Diagnostic Procedures.

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