| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Mouse, Human |
| Target | PUR1, PURA, Purine-rich single-stranded DNA-binding protein alpha, Transcriptional activator protein Pur-alpha |
| Immunogen | E. coli - derived recombinant Human PURA (Gln59-Tyr209). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | Q00577 |
| Background | Transcriptional activator protein Pur-alpha (PURA) is a ~34 kDa protein. This is a probable transcription activator that specifically binds the purine-rich single strand of the PUR element located upstream of the MYC gene. May play a role in the initiation of DNA replication and in recombination. 1. Bergemann, AD. et al. (1992) Molecular and cellular biology 12, 5673-82. PMID: 1448097 2. Graebsch, A. et al. (2010) PloS one 5, e13402. PMID: 20976240 |
| Note | For research use only |