Anti-Human CACNA1B Polyclonal Antibody

Form	Liquid
Host Species	Rabbit
Clonality	Polyclonal
Isotype	IgG
Purification	Purified by antigen affinity column.
Endotoxin Level	Please contact with the lab for this information.
Applications	ELISA, IHC, WB
Species Reactivity	Rat, Mouse, Human
Target	BIII, Brain calcium channel III, CACH5, CACNA1B, CACNL1A5, Calcium channel, L type, alpha-1 polypeptide isoform 5, Voltage-dependent N-type calcium channel subunit alpha-1B, Voltage-gated calcium chan
Immunogen	E. coli - derived recombinant Human CACNA1B (Gly1722-Gln1875).
Storage Buffer	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage Information	ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession Number	Q00975
Background	Voltage-dependent N-type calcium channel subunit alpha-1B (CACNA1B) is a ~262 kDa protein. Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This alpha-1B subunit gives rise to N-type calcium currents. N-type calcium channels belong to the 'high-voltage activated' (HVA) group. They are involved in pain signaling. Calcium channels containing alpha-1B subunit may play a role in directed migration of immature neurons. 1. Groen, JL. et al. (2015) Human molecular genetics 24, 987-93. PMID: 25296916
Note	For research use only

For Research Use Only. Not for Diagnostic Procedures.

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