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Anti-Mouse SORD Polyclonal Antibody

  • Cat. No.:RB9TMX841014
  • Price:Negotiable
  • Clicks:454

Product Detail

Product Parameters

FormLiquid
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by antigen affinity column.
Endotoxin LevelPlease contact with the lab for this information.
ApplicationsELISA, IHC, WB
Species ReactivityRat, Mouse
Target(R,R)-butanediol dehydrogenase, EC:1.1.1.-, EC:1.1.1.14, EC:1.1.1.4, EC:1.1.1.56, EC:1.1.1.9, L-iditol 2-dehydrogenase, Polyol dehydrogenase, RDH, Ribitol dehydrogenase, SDH, SORD, Sorbitol dehydrogen
ImmunogenE. coli - derived recombinant Mouse SORD (Met1-Pro357).
Storage Buffer0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage InformationELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession NumberQ64442
Background

Sorbitol dehydrogenase (SORD) is a ~38 kDa protein. Polyol dehydrogenase that catalyzes the reversible NAD(+)-dependent oxidation of various sugar alcohols. Is active with D-sorbitol (D-glucitol) leading to the C2-oxidized product D-fructose. Is a key enzyme in the polyol pathway that interconverts glucose and fructose via sorbitol, which constitutes an important alternate route for glucose metabolism. May play a role in sperm motility by using sorbitol as an alternative energy source for sperm motility and protein tyrosine phosphorylation. Has no activity on ethanol.

1. Burnell, JN. et al. (1983) The International journal of biochemistry 15, 507-11. PMID: 6852349
2. Cao, W. et al. (2009) Biology of reproduction 80, 124-33. PMID: 18799757
NoteFor research use only
For Research Use Only. Not for Diagnostic Procedures.

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