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Anti-Mouse IGF1 Polyclonal Antibody

  • Cat. No.:RB9TMY095014
  • Price:Negotiable
  • Clicks:470

Product Detail

Product Parameters

FormLiquid
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by antigen affinity column.
Endotoxin LevelPlease contact with the lab for this information.
ApplicationsELISA, IHC, WB
Species ReactivityRat, Human, Mouse
TargetIBP1, IGF-1, IGF-I, IGF1, Insulin-like growth factor 1, Insulin-like growth factor I, MGF, Mechano growth factor, Somatomedin-C
ImmunogenE. coli - derived recombinant Mouse IGF1 (Val65-Lys134).
Storage Buffer0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage InformationELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession NumberP05017
Background

Insulin-like growth factor 1 (IGF1) is a ~17 kDa protein. The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exocytosis of IGF1 is required for sensory perception of smell in the olfactory bulb.

1. Cao, P. et al. (2011) Cell 145, 300-11. PMID: 21496647
NoteFor research use only
For Research Use Only. Not for Diagnostic Procedures.

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