Anti-Mouse PLA2G1B Polyclonal Antibody
- Cat. No.：RB9TMY504014
- Price：Negotiable
- Clicks：538
Product Detail
Product Parameters
| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Mouse |
| Target | EC:3.1.1.4, Group IB phospholipase A2, PLA2, PLA2A, PLA2G1B, PPLA2, Phosphatidylcholine 2-acylhydrolase 1B, Phospholipase A2 |
| Immunogen | E. coli - derived recombinant Mouse PLA2G1B (Ser20-Cys146). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | Q9Z0Y2 |
| Background | Phospholipase A2 (PLA2G1B) is a ~16 kDa protein. Secretory calcium-dependent phospholipase A2 that primarily targets dietary phospholipids in the intestinal tract. Hydrolyzes the ester bond of the fatty acyl group attached at sn-2 position of phospholipids (phospholipase A2 activity) with preference for phosphatidylethanolamines and phosphatidylglycerols over phosphatidylcholines. May play a role in the biosynthesis of N-acyl ethanolamines that regulate energy metabolism and inflammation in the intestinal tract. Hydrolyzes N-acyl phosphatidylethanolamines to N-acyl lysophosphatidylethanolamines, which are further cleaved by a lysophospholipase D to release N-acyl ethanolamines. May act in an autocrine and paracrine manner. 1. Cupillard, L. et al. (1999) The Journal of biological chemistry 274, 7043-51. PMID: 10066760 2. Entwistle, LJ. et al. (2017) Cell host & microbe 22, 484-493.e5. PMID: 29024642 |
| Note | For research use only |
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