Anti-Streptococcus pneumoniae psaA Polyclonal Antibody

Form	Liquid
Host Species	Rabbit
Clonality	Polyclonal
Isotype	IgG
Purification	Purified by antigen affinity column.
Endotoxin Level	Please contact with the lab for this information.
Applications	ELISA, IHC, WB
Species Reactivity	Streptococcus pneumoniae, Streptococcus oralis, Streptococcus pneumoniae serotype 4, Streptococcus anginosus, Streptococcus mitis
Target	Manganese ABC transporter substrate-binding lipoprotein PsaA, Pneumococcal surface adhesin A, psaA
Immunogen	E. coli - derived recombinant Streptococcus pneumoniae psaA (Lys34-Lys309).
Storage Buffer	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage Information	ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession Number	P0A4G2
Background	Manganese ABC transporter substrate-binding lipoprotein PsaA is a ~34 kDa protein. Part of the ATP-binding cassette (ABC) transport system PsaABC involved in manganese import. Binds manganese with high affinity and specificity and delivers it to the membrane permease for translocation into the cytoplasm. Also acts as an adhesin which is involved on adherence to extracellular matrix. It is an important factor in pathogenesis and infection. 1. McDevitt, CA. et al. (2011) PLoS pathogens 7, e1002357. PMID: 22072971 2. Dintilhac, A. et al. (1997) Molecular microbiology 25, 727-39. PMID: 9379902
Note	For research use only

For Research Use Only. Not for Diagnostic Procedures.

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