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Anti-Streptococcus pneumoniae psaA Polyclonal Antibody

  • Cat. No.:RB9TJN184044
  • Price:Negotiable
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Product Detail

Product Parameters

FormLiquid
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by antigen affinity column.
Endotoxin LevelPlease contact with the lab for this information.
ApplicationsELISA, IHC, WB
Species ReactivityStreptococcus pneumoniae, Streptococcus oralis, Streptococcus pneumoniae serotype 4, Streptococcus anginosus, Streptococcus mitis
TargetManganese ABC transporter substrate-binding lipoprotein PsaA, Pneumococcal surface adhesin A, psaA
ImmunogenE. coli - derived recombinant Streptococcus pneumoniae psaA (Lys34-Lys309).
Storage Buffer0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage InformationELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession NumberP0A4G2
Background

Manganese ABC transporter substrate-binding lipoprotein PsaA is a ~34 kDa protein. Part of the ATP-binding cassette (ABC) transport system PsaABC involved in manganese import. Binds manganese with high affinity and specificity and delivers it to the membrane permease for translocation into the cytoplasm. Also acts as an adhesin which is involved on adherence to extracellular matrix. It is an important factor in pathogenesis and infection.

1. McDevitt, CA. et al. (2011) PLoS pathogens 7, e1002357. PMID: 22072971
2. Dintilhac, A. et al. (1997) Molecular microbiology 25, 727-39. PMID: 9379902
NoteFor research use only
For Research Use Only. Not for Diagnostic Procedures.

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