| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Streptococcus pneumoniae, Streptococcus oralis, Streptococcus pneumoniae serotype 4, Streptococcus anginosus, Streptococcus mitis |
| Target | Manganese ABC transporter substrate-binding lipoprotein PsaA, Pneumococcal surface adhesin A, psaA |
| Immunogen | E. coli - derived recombinant Streptococcus pneumoniae psaA (Lys34-Lys309). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | P0A4G2 |
| Background | Manganese ABC transporter substrate-binding lipoprotein PsaA is a ~34 kDa protein. Part of the ATP-binding cassette (ABC) transport system PsaABC involved in manganese import. Binds manganese with high affinity and specificity and delivers it to the membrane permease for translocation into the cytoplasm. Also acts as an adhesin which is involved on adherence to extracellular matrix. It is an important factor in pathogenesis and infection. 1. McDevitt, CA. et al. (2011) PLoS pathogens 7, e1002357. PMID: 22072971 2. Dintilhac, A. et al. (1997) Molecular microbiology 25, 727-39. PMID: 9379902 |
| Note | For research use only |