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Anti-Mouse CTSG Polyclonal Antibody

  • Cat. No.:RB9TMY284014
  • Price:Negotiable
  • Clicks:278

Product Detail

Product Parameters

FormLiquid
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by antigen affinity column.
Endotoxin LevelPlease contact with the lab for this information.
ApplicationsELISA, IHC, WB
Species ReactivityMouse
TargetCathepsin G, Ctsg, EC:3.4.21.20, VSP, Vimentin-specific protease
ImmunogenE. coli - derived recombinant Mouse CTSG (Met35-Pro247).
Storage Buffer0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage InformationELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession NumberP28293
Background

Cathepsin G (CTSG) is a ~29 kDa protein. Serine protease with trypsin- and chymotrypsin-like specificity. Also displays antibacterial activity against Gram-negative and Gram-positive bacteria independent of its protease activity. Prefers Phe and Tyr residues in the P1 position of substrates but also cleaves efficiently after Trp and Leu. Shows a preference for negatively charged amino acids in the P2' position and for aliphatic amino acids both upstream and downstream of the cleavage site. Required for recruitment and activation of platelets which is mediated by the F2RL3/PAR4 platelet receptor.

1. Nakamura, N. et al. (1992) European journal of biochemistry 205, 947-54. PMID: 1577012
NoteFor research use only
For Research Use Only. Not for Diagnostic Procedures.

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