Anti-Mouse CFB Polyclonal Antibody
- Cat. No.：RB9TMF634014
- Price：Negotiable
- Clicks：255
Product Detail
Product Parameters
| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Mouse |
| Target | Bf, C3/C5 convertase, Cfb, Complement factor B, Complement factor B Ba, Complement factor B Bb, EC:3.4.21.47, H2-Bf |
| Immunogen | E. coli - derived recombinant Mouse CFB (Gly484-Leu761). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | P04186 |
| Background | Complement factor B (CFB) is a ~85 kDa protein. Precursor of the catalytic component of the C3 and C5 convertase complexes of the alternative pathway of the complement system, a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system. The alternative complement pathway acts as an amplification loop that enhances other complement pathways (classical, lectin and GZMK) by promoting formation of additional C3 and C5 convertases. CFB is cleaved and activated by CFD to generate Ba and Bb chains; Bb chain constituting the catalytic component of the C3 and C5 convertases. |
| Note | For research use only |
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