Anti-Mouse FGA Polyclonal Antibody
- Cat. No.：RB9TMF809014
- Price：Negotiable
- Clicks：226
Product Detail
Product Parameters
| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Human, Mouse, Rat |
| Target | Fga, Fibrinogen alpha chain, Fibrinopeptide A |
| Immunogen | E. coli - derived recombinant Mouse FGA (Thr552-Gln789). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | E9PV24 |
| Background | Fibrinogen alpha chain (FGA) is a ~87 kDa protein. Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta (FGB) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. 1. Suh, TT. et al. (1995) Genes & development 9, 2020-33. PMID: 7649481 2. Drew, AF. et al. (2001) Blood 97, 3691-8. PMID: 11389004 3. Ni, H. et al. (2000) The Journal of clinical investigation 106, 385-92. PMID: 10930441 4. Yang, H. et al. (2009) Blood 114, 425-36. PMID: 19332769 5. Johnson, LL. et al. (2003) The Journal of experimental medicine 197, 801-6. PMID: 12629066 6. Luo, D. et al. (2013) Journal of immunology (Baltimore, Md. : 1950) 190, 4149-61. PMID: 23487423 |
| Note | For research use only |
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