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Anti-Mouse CD166/ALCAM Polyclonal Antibody

  • Cat. No.:RB9TMC678014
  • Price:Negotiable
  • Clicks:490

Product Detail

Product Parameters

FormLiquid
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by antigen affinity column.
Endotoxin LevelPlease contact with the lab for this information.
ApplicationsELISA, IHC, WB
Species ReactivityMouse, Rat
TargetActivated leukocyte cell adhesion molecule, Alcam, BEN, CD166, CD166 antigen, Protein DM-GRASP
ImmunogenE. coli - derived recombinant Mouse CD166/ALCAM (Thr30-Ile233).
Storage Buffer0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage InformationELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession NumberQ61490
Background

CD166 antigen (ALCAM) is a ~65 kDa protein. Cell adhesion molecule that mediates both heterotypic cell-cell contacts via its interaction with CD6, as well as homotypic cell-cell contacts. Promotes T-cell activation and proliferation via its interactions with CD6. Contributes to the formation and maturation of the immunological synapse via its interactions with CD6. Mediates homotypic interactions with cells that express ALCAM. Mediates attachment of dendritic cells onto endothelial cells via homotypic interaction.

1. Chitteti, BR. et al. (2014) Blood 124, 519-29. PMID: 24740813
2. Iolyeva, M. et al. (2013) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 27, 978-90. PMID: 23169771
3. Hooker, RA. et al. (2015) Journal of musculoskeletal & neuronal interactions 15, 83-94. PMID: 25730656
4. Weiner, JA. et al. (2004) Molecular and cellular neurosciences 27, 59-69. PMID: 15345243
NoteFor research use only
For Research Use Only. Not for Diagnostic Procedures.

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