| Form | Liquid |
|---|---|
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification | Purified by antigen affinity column. |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, IHC, WB |
| Species Reactivity | Mouse, Rat |
| Target | Activated leukocyte cell adhesion molecule, Alcam, BEN, CD166, CD166 antigen, Protein DM-GRASP |
| Immunogen | E. coli - derived recombinant Mouse CD166/ALCAM (Thr30-Ile233). |
| Storage Buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| Product Usage Information | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| Accession Number | Q61490 |
| Background | CD166 antigen (ALCAM) is a ~65 kDa protein. Cell adhesion molecule that mediates both heterotypic cell-cell contacts via its interaction with CD6, as well as homotypic cell-cell contacts. Promotes T-cell activation and proliferation via its interactions with CD6. Contributes to the formation and maturation of the immunological synapse via its interactions with CD6. Mediates homotypic interactions with cells that express ALCAM. Mediates attachment of dendritic cells onto endothelial cells via homotypic interaction. 1. Chitteti, BR. et al. (2014) Blood 124, 519-29. PMID: 24740813 2. Iolyeva, M. et al. (2013) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 27, 978-90. PMID: 23169771 3. Hooker, RA. et al. (2015) Journal of musculoskeletal & neuronal interactions 15, 83-94. PMID: 25730656 4. Weiner, JA. et al. (2004) Molecular and cellular neurosciences 27, 59-69. PMID: 15345243 |
| Note | For research use only |