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Anti-Mouse CD13/ANPEP Polyclonal Antibody

  • Cat. No.:RB9TMB650014
  • Price:Negotiable
  • Clicks:470

Product Detail

Product Parameters

FormLiquid
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by antigen affinity column.
Endotoxin LevelPlease contact with the lab for this information.
ApplicationsELISA, IHC, WB
Species ReactivityMouse
TargetAP-M, AP-N, Alanyl aminopeptidase, Aminopeptidase M, Aminopeptidase N, Anpep, CD13, EC:3.4.11.2, Lap-1, Lap1, Membrane protein p161, Microsomal aminopeptidase, mAPN
ImmunogenE. coli - derived recombinant Mouse CD13/ANPEP (Thr79-Glu285).
Storage Buffer0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Product Usage InformationELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession NumberP97449
Background

Aminopeptidase N (CD13/ANPEP) is a ~109 kDa protein. Broad specificity aminopeptidase which plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Also involved in the processing of various peptides including peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. May also be involved the cleavage of peptides bound to major histocompatibility complex class II molecules of antigen presenting cells. May have a role in angiogenesis and promote cholesterol crystallization. May have a role in amino acid transport by acting as binding partner of amino acid transporter SLC6A19 and regulating its activity.

1. Larsen, SL. et al. (1996) The Journal of experimental medicine 184, 183-9. PMID: 8691132
2. Fairweather, SJ. et al. (2012) The Biochemical journal 446, 135-48. PMID: 22677001
NoteFor research use only
For Research Use Only. Not for Diagnostic Procedures.

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